viruses in faeces

Virome Analysis

Most traditional diagnostic tools in virology target a single virus specifically and allow only a very limited insight into the entirety of viruses present in a given environment, the so-called “virome”. New unspecific sequencing techniques such as next generation sequencing (NGS) have revolutionised virome analysis and allow a comprehensive overview of the virome. Embracing these new techniques, the virome research group investigates the virome of different animal species - with emphasis on livestock animals - in two major but interlinked directions: i) on the applied side, the development of virome analysis for the diagnostic use in veterinary virology is a major topic as it allows detection of all viruses present even “new” or mutated ones in a single test; ii) on the basic research side, the study of the mechanisms involved in the complex interactions within the virome as well as with “cohabitants” like bacteria, fungi or protozoa and the influence these have on the host may provide new aspects of how viruses influence the health status of their hosts.


Cover Illustration: Electronmicrograph of virusparticles in faeces