Publications

2022

Frequent Occurrence of Simultaneous Infection with Multiple Rotaviruses in Swiss Pigs.
Sibylle Baumann, Titus Sydler, Giuliana Rosato, Monika Hilbe, Dolf Kümmerlen, Xaver Sidler, Claudia Bachofen; Viruses 2022, 14(5), 1117; https://doi.org/10.3390/v14051117

2021

An Evaluation of Hepatitis E Virus Molecular Typing Methods

Sally A Bayli, Cornelia Adlhoch, Liam Childs, and the HEV Sequencing Study Group
Clin Chem. 2021 Dec 30;68(1):181-191. doi: 10.1093/clinchem/hvab186.
 

Benchmark of thirteen bioinformatic pipelines for metagenomic virus diagnostics using datasets from clinical samples

Jutte J C de VriesJulianne R BrownNicole FischerIgor A SidorovSofia MorfopoulouJiabin HuangBas B Oude MunninkArzu SayinerAlihan BulgurcuChristophe RodriguezGuillaume GricourtEls Keyaerts, Leen BellerClaudia BachofenJakub Kubacki,  Cordey SamuelLaubscher Florian, Schmitz DennisMartin Beer, Dirk HoeperMichael HuberVerena KufnerMaryam ZaheriAitana LebrandAnna PapaSander van BoheemenAloys C M KroesJudith BreuerF Xavier Lopez-LabradorEric C J Claas 
J Clin Virol. 2021 Aug;141:104908.doi:10.1016/j.jcv.2021.104908

 

Benefit of Bovine Viral Diarrhoea (BVD) Eradication in Cattle on Pestivirus Seroprevalence in Sheep

Andrea Franziska Huser , Jessica Grace SchärClaudia BachofenElena de Martin, Jasmine PortmannHanspeter StalderMatthias Schweizer 
Front Vet Sci. 2021 Oct 4;8:681559. doi: 10.3389/fvets.2021.681559

 

Genome Sequence of Equid Alphaherpesvirus 1 (EHV-1) from a Nasal Swab of Swiss Hose Associated with a Major EHV-1 Outbreak following a Show Jumbing Event in Valencia, Spain
Jakub Kubacki, Julia Lechmann, Cornel Fraefel, Claudia Bachofen
Microbiol Resour Announc. 2021 Aug 26;10(34):e0073221.doi:10.1128/MRA.00732-21

 

Genetic Diversity of Hepatitis E Virus Type 3 in Switzerland—From Stable to Table
Isabelle Vonlanthen-Specker, Roger Stephan, Xaver Sidler, Dominik Moor, Cornel Fraefel, Claudia Bachofen
Animals (Basel). 2021 Nov 7;11(11):3177.doi:10.3390/ani11113177

 

Development of a recombinant ELISA for ovine herpersvirus 2, suitable for use in sheep
George C. Russell, Ann Percial, Dawn M. Grant, Kathryn Bartley, Dylan Turbull, Kevin McLean, Julia Lienahrd, Claudia Bachofen
J Virol Methods, 2022 Jan; 299:114329.doi:10.1016/j.Jviromet.2021.114329

 

Screening of Swiss Pig Herds for Hepatitis E Virus: A Pilot Study
Julia Lienhard, Isabelle Vonlanthen-Specker, Xaver Sidler, Claudia Bachofen

Animals 2021, 11(11), 3050; https://doi.org/10.3390/ani11113050

 

Prevalence of Nasal Shedding of Equid Gammaherpesviruses in Healthy Swiss Horses

Laura Scheurer, Claudia Bachofen, Isabelle Hardmeier, Julia Lechmann, Angelika Schoster

Viruses 2021, 13(9), 1686; https://doi.org/10.3390/v13091686 (registering DOI)

 

Viral infections shared between water buffaloes and small ruminants in Switzerland

Lechmann, Mathias Ackermann, Vanessa Kaiser, Claudia Bachofen

 

Porcine teschovirus, sapelovirus, and enterovirus in Swiss pigs: multiplex RT-PCR investigation of viral frequencies and disease association

Tamara Stäubli, Charlotte Rickli, Paul R. Torgerson, Cornel Fraefel, Julia Lechmann

Porcine teschovirus, sapelovirus, and enterovirus in Swiss pigs: multiplex RT-PCR investigation of viral frequencies and disease association

Tamara Stäubli, Charlotte Rickli, Paul R. Torgerson, Cornel Fraefel, Julia Lechmann

Recommendations for the introduction of metagenomic next-generation sequencing in clinical virology, part II: bioinformatic analysis and reporting. 
de Vries JJC, Brown JR, Couto N, Beer M, Le Mercier P, Sidorov I, Papa A, Fischer N, Oude Munnink BB, Rodriquez C, Zaheri M, Sayiner A, Hönemann M, Cataluna AP, Carbo EC, Bachofen C, Kubacki J, Schmitz D, Tsioka K, Matamoros S, Höper D, Hernandez M, Puchhammer-Stöckl E, Lebrand A, Huber M, Simmonds P, Claas ECJ, López-Labrador FX; ESCV Network on Next-Generation Sequencing.
J Clin Virol. 2021 May;138:104812. doi: 10.1016/j.jcv.2021.104812.

 

Active equine parvovirus-hepatitis infection is most frequently detected in Austrian horses of advanced age

Marcha Badenhorst, Phebe de Heus, Angelika Auer, Birthe Tegtmeyer, Alexander Stang, Katharina Dimmel, Alexander Tichy, Jakub Kubacki, Claudia Bachofen, Eike Steinmann, Jessika M.V. Cavalleri

Equine Vet J. 2021 Mar 11. doi: 10.1111/evj.13444

2020

Bovine viral diarrhoea virus loses quasispecies diversity rapidly in culture.

George C Russell, Ruth N Zadoks, Kim Willoughby, Claudia Bachofen

 

Rapid and simple colorimetric loop-mediated isothermal amplification
(LAMP) assay for the detection of Bovine alphaherpesvirus 1

Deborah Peltzer, Kurt Tobler, Cornel Fraefel, Madeleine Maley, Claudia Bachofen

 

Implementation of next-generation sequencing as a diagnostic tool in veterinary virology (PDF, 835 KB)

Kubacki Jakub, Fraefel, Cornel, Bachofen Claudia

Journal of Veterinary Diagnostic Investigation 2020 19-0521.R1

 

Seroprevalence of hepatits E virus in dogs in Switzerland
Rebecca Veronesi, Marina Morach, Ella Hübschke, Claudia Bachofen, Roger Stephan, Magdalena Nüesch-Inderbinen

 

Feldversuch zur Eradikation von Methicillin-resistenten Staphylococcus aureus (MRSA) mittels Bakteriophagen in einem Schweinezuchtbetrieb

Honegger J, Lehnherr H. Bachofen C. Stephan R. Sidler X

Schweiz Arch Tierheilkd. 2020 May;162(5):307-317. doi: 10.17236/sat00259.

 

A case series highlighting the role of different gamma-herpesviruses in Equine Multinodular Pulmonary Fibrosis

Scheurer L, Bachofen C, Herteman N, Hilbe M, Wolfer N, Schoster A.

Schweiz Arch Tierheilkd. 2020 Apr;162(4):245-256. doi: 10.17236/sat00255.

 

2019

A novel PCR protocol for detection and differentiation of neuropathogenic and non-neuropathogenic equid alphaherpesvirus 1

Julia Lechmann, Angelika Schoster, Martina Ernstberger, Nathalie Fouché, Cornel Fraefel, Claudia Bachofen

J Virol. 2019 Oct 16. pii: JVI.01110-19. doi: 10.1128/JVI.01110-19

 

HEVnet: a One Health, collaborative, interdisciplinary network and sequence data repository for enhanced hepatitis E virus molecular typing, characterisation and
epidemiological investigations.

Annemieke Christine Mulder, Annelies Kroneman, Eelco Franz, Harry Vennema, Anna D. Tulen, Johanna Takkinen, Agnetha Hofhuis, Cornelia Adlhoch, Members of HEVnet

Euro Surveill. 2019;24(10):pii=1800407. https://doi.org/10.2807/1560-7917.ES.2019.24.10.1800407

 

Confirmation of Tick-borne encephalitis virus in an European hedgehog (Erinaceus europaeus).

Schönbächler K, Hatt J, Silaghi C, Merz N, Fraefel C, Bachofen C.

Schweiz Arch Tierheilkd. 2019 Jan;161(1):23-31. doi: 10.17236/sat00191.

2018

Traces of history conserved over 600 years in the geographic distribution of genetic variants of an RNA virus: Bovine viral diarrhea virus in Switzerland.

Hanspeter Stalder, Claudia Bachofen, Matthias Schweizer, Reto Zanoni, Dominik Sauerländer, Ernst Peterhans.

PLoS One. 2018 Dec 5;13(12):e0207604. doi: 10.1371/journal.pone.0207604. eCollection 2018.

 

Complete Genome Sequence of a Swiss Hepatitis E Virus Isolate from the Liver of a Fattening Pig.

Wist V, Kubacki J, Lechmann J, Steck M, Fraefel C, Stephan R, Bachofen C.

Genome Announc. 2018 Mar 1;6(9). pii: e00113-18. doi: 10.1128/genomeA.00113-18.

 

Complete Genome Sequences of Two Swiss Hepatitis E Virus Isolates from Human Stool and Raw Pork Sausage.

Kubacki J, Fraefel C, Jermini M, Giannini P, Martinetti G, Ripellino P, Bernasconi E, Sidler X, Stephan R, Bachofen C.

Genome Announc. 2017 Aug 31;5(35). pii: e00888-17. doi: 10.1128/genomeA.00888-17. PMID:28860248

 

 

Analysis of bovine viral diarrhoea virus: Biobank and sequence database to support eradication in Scotland.

Russell GC, Grant DM, Lycett S, Bachofen C, Caldow GL, Burr PD, Davie K, Ambrose N, Gunn GJ, Zadoks RN.

Vet Rec. 2017 May 6;180(18):447. doi: 10.1136/vr.104072. Epub 2017 Apr 6. PMID:28386029

 

Assessment of the rabbit as a wildlife reservoir of bovine viral diarrhea virus: serological analysis and generation of trans-placentally infected offspring.

Grant DM, Dagleish MP, Bachofen C, Boag B, Deane D, Percival A, Zadoks RN, Russell GC.

Front Microbiol. 2015 Sep 23;6:1000. doi: 10.3389/fmicb.2015.01000. eCollection 2015.

 

A nationwide database linking information on the hosts with sequence data of their virus strains: A useful tool for the eradication of bovine viral diarrhea (BVD) in Switzerland.

Stalder H, Hug C, Zanoni R, Vogt HR, Peterhans E, Schweizer M, Bachofen C.

Virus Res. 2016 Jun 15;218:49-56. doi: 10.1016/j.virusres.2015.09.012. Epub 2015 Sep 25.

 

Complete Genome Sequence of a Bovine Viral Diarrhea Virus Subgenotype 1e Strain Isolated in Switzerland.

Stalder H, Schweizer M, Bachofen C.

Genome Announc. 2015 Jun 11;3(3). pii: e00636-15. doi: 10.1128/genomeA.00636-15.

 

Specificity of pestivirus antibodies in wild ruminants from Switzerland.

Fernández-Sirera L, Casaubon J, Ryser-Degiorgis MP, Vogt HR, Marco I, Peterhans E, Bachofen C.

Schweiz Arch Tierheilkd. 2014 Jul;156(7):349-51. doi: 10.1024/0036-7281/a000606. No abstract available.

 

Experimental infection of rabbits with bovine viral diarrhoea virus by a natural route of exposure.

Bachofen C, Grant DM, Willoughby K, Zadoks RN, Dagleish MP, Russell GC.

Vet Res. 2014 Apr 2;45:34. doi: 10.1186/1297-9716-45-34.

 

[Bovine viral diarrhea (BVD): from biology to control].

Bachofen C, Stalder H, Vogt HR, Wegmüller M, Schweizer M, Zanoni R, Peterhans E.

Berl Munch Tierarztl Wochenschr. 2013 Nov-Dec;126(11-12):452-61. German.

 

Sheep persistently infected with Border disease readily transmit virus to calves seronegative to BVD virus.

Braun U, Reichle SF, Reichert C, Hässig M, Stalder HP, Bachofen C, Peterhans E.

Vet Microbiol. 2014 Jan 10;168(1):98-104. doi: 10.1016/j.vetmic.2013.11.004. Epub 2013 Nov 15.

 

Diagnostic gap in Bovine viral diarrhea virus serology during the periparturient period in cattle.

Bachofen C, Bollinger B, Peterhans E, Stalder H, Schweizer M.

J Vet Diagn Invest. 2013 Sep;25(5):655-61. doi: 10.1177/1040638713501172.

 

Persistent infections after natural transmission of bovine viral diarrhoea virus from cattle to goats and among goats.

Bachofen C, Vogt HR, Stalder H, Mathys T, Zanoni R, Hilbe M, Schweizer M, Peterhans E.

Vet Res. 2013 May 15;44:32. doi: 10.1186/1297-9716-44-32.

 

Investigation of border disease and bovine virus diarrhoea in sheep from 76 mixed cattle and sheep farms in eastern Switzerland.

Braun U, Bachofen C, Schenk B, Hässig M, Peterhans E.

Schweiz Arch Tierheilkd. 2013 May;155(5):293-8. doi: 10.1024/0036-7281/a000460.

 

Direct RT-PCR from serum enables fast and cost-effective phylogenetic analysis of bovine viral diarrhoea virus.

Bachofen C, Willoughby K, Zadoks R, Burr P, Mellor D, Russell GC.

J Virol Methods. 2013 Jun;190(1-2):1-3. doi: 10.1016/j.jviromet.2013.03.015. Epub 2013 Mar 26.

 

Infection of cattle with Border disease virus by sheep on communal alpine pastures.

Braun U, Bachofen C, Büchi R, Hässig M, Peterhans E.

Schweiz Arch Tierheilkd. 2013 Feb;155(2):123-8. doi: 10.1024/0036-7281/a000428.

 

Apoptosis in Bovine viral diarrhea virus (BVDV)-induced mucosal disease lesions: a histological, immunohistological, and virological investigation.

Hilbe M, Girao V, Bachofen C, Schweizer M, Zlinszky K, Ehrensperger F.

Vet Pathol. 2013 Jan;50(1):46-55. doi: 10.1177/0300985812447826. Epub 2012 Jun 14.

 

Cytopathic bovine viral diarrhea viruses (BVDV): emerging pestiviruses doomed to extinction.

Peterhans E, Bachofen C, Stalder H, Schweizer M.

Vet Res. 2010 Nov-Dec;41(6):44. doi: 10.1051/vetres/2010016. Epub 2010 Mar 4. Review.

 

Clinical appearance and pathology of cattle persistently infected with bovine viral diarrhoea virus of different genetic subgroups.

Bachofen C, Braun U, Hilbe M, Ehrensperger F, Stalder H, Peterhans E.

Vet Microbiol. 2010 Mar 24;141(3-4):258-67. doi: 10.1016/j.vetmic.2009.09.022. Epub 2009 Sep 25.

 

Co-existence of genetically and antigenically diverse bovine viral diarrhoea viruses in an endemic situation.

Bachofen C, Stalder H, Braun U, Hilbe M, Ehrensperger F, Peterhans E.

Vet Microbiol. 2008 Sep 18;131(1-2):93-102. doi: 10.1016/j.vetmic.2008.02.023. Epub 2008 Mar 4.

 

Genetic heterogeneity of pestiviruses of ruminants in Switzerland.

Stalder HP, Meier P, Pfaffen G, Wageck-Canal C, Rüfenacht J, Schaller P, Bachofen C, Marti S, Vogt HR, Peterhans E.

Prev Vet Med. 2005 Nov 15;72(1-2):37-41; discussion 215-9. Epub 2005 Oct 6.