Selected Publications

1. Novel Mutant AAV2 Rep Proteins Support AAV2 Replication without Blocking HSV-1 Helpervirus Replication. Seyffert M, Glauser DL, Schraner EM, de Oliveira AP, Mansilla-Soto J, Vogt B, Büning H, Linden RM, Ackermann M, Fraefel C. PLoS One. 2017 Jan 26;12(1):e0170908. doi: 10.1371/journal.pone.0170908.

2. Adeno-Associated Virus Type 2 Rep68 Can Bind to Consensus Rep-Binding Sites on the Herpes Simplex Virus 1 Genome. Seyffert M, Glauser DL, Tobler K, Georgiev O, Vogel R, Vogt B, Agúndez L, Linden M, Büning H, Ackermann M, Fraefel C. J Virol. 2015 Nov;89(21):11150-8. doi: 10.1128/JVI.01370-15.

3. Viral and Cellular Components of AAV2 Replication Compartments. Vogel R, Seyffert M, Pereira Bde A, Fraefel C. Open Virol J. 2013 Oct 31;7:98-120. doi: 10.2174/1874357901307010098.

4. Adeno-associated virus type 2 modulates the host DNA damage response induced by herpes simplex virus 1 during coinfection. Definition of herpes simplex virus type 1 helper activities for adeno-associated virus early replication events. Alazard-Dany N, Nicolas A, Ploquin A, Strasser R, Greco A, Epstein AL, Fraefel C, Salvetti A. PLoS Pathog. 2009 Mar;5(3):e1000340. doi: 10.1371/journal.ppat.1000340.

5. Inhibition of herpes simplex virus type 1 replication by adeno-associated virus rep proteins depends on their combined DNA-binding and ATPase/helicase activities. Glauser DL, Seyffert M, Strasser R, Franchini M, Laimbacher AS, Dresch C, de Oliveira AP, Vogel R, Büning H, Salvetti A, Ackermann M, Fraefel C. J Virol. 2010 Apr;84(8):3808-24. doi: 10.1128/JVI.01503-09.

6. Vogel R, Seyffert M, Strasser R, de Oliveira AP, Dresch C, Glauser DL, Jolinon N, Salvetti A, Weitzman MD, Ackermann M, Fraefel C. J Virol. 2012 Jan;86(1):143-55. doi: 10.1128/JVI.05694-11.

7. Live covisualization of competing adeno-associated virus and herpes simplex virus type 1 DNA replication: molecular mechanisms of interaction. Glauser DL, Strasser R, Laimbacher AS, Saydam O, Clément N, Linden RM, Ackermann M, Fraefel C. J Virol. 2007 May;81(9):4732-43.

8. Four-dimensional visualization of the simultaneous activity of alternative adeno-associated virus replication origins. Glauser DL, Saydam O, Balsiger NA, Heid I, Linden RM, Ackermann M, Fraefel C.

J Virol. 2005 Oct;79(19):12218-30

9. Spatial and temporal organization of adeno-associated virus DNA replication in live cells.

Fraefel C, Bittermann AG, Büeler H, Heid I, Bächi T, Ackermann M. J Virol. 2004 Jan;78(1):389-98.