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2025

Comparative analysis of NSP5/VP2-induced viroplasm-like structures in rotavirus species A to J
Cosic A., Lee M., Tobler K., Aguilar C., Fraefel C., Eichwald C., 2025.
Journal of Virology, Vol. 99, No. 11; doi: 10.1128/jvi.00990-25

The influence of the cytoskeleton on the development and behavior of viral factories in mammalian orthoreovirus
Lee, M., Vetter, J., Eichwald, C., 2025.
Virology, Vol. 604; doi: 10.1016/j.virol.2025.110423

2024

Characterization of viroplasm-like structures by co-expression of NSP5 and NSP2 across rotavirus species A to J
Lee, M., Cosic, A., Tobler, K., Aguilar, C., Fraefel, C., Eichwald, C., 2024.
Journal of Virology, Vol. 98, No. 9; doi: 10.1128/jvi.00975-24

Antibody reactions of horses against various domains of EHV-1 receptor-binding protein gD1
Schramm, A., Ackermann, M., Eichwald, C., Aguilar, C., Fraefel, C., Lechmann, J., 2024.
Plos ONE, 19(7): e0301987; doi: 10.1371/journal.pone.030198
7

The recruitment of TRiC chaperonin in rotavirus viroplasms correlates with virus replication
Vetter, J., Papa, G., Tobler, K., Rodriguez Javier, M., Kley, M., Myers, M., Wiesendanger, M., Schraner Elisabeth, M., Luque, D., Burrone Oscar, R., Fraefel, C., Eichwald, C., 2024.
mBio 15(4): e00499-00424. doi: 10.1128/mbio.00499-24

The Role of the Host Cytoskeleton in the Formation and Dynamics of Rotavirus Viroplasms
Vetter, J., Lee, M., Eichwald, C., 2024.
Viruses 16(5):668. doi:10.3390/v16050668

2022

Lipid metabolism is involved in the association of rotavirus viroplasms with endoplasmic reticulum membranes
Martínez, J.L., Eichwald, C., Schraner, E.M., López, S., Arias, C.F., 2022.
Virology 569, 29-36. doi: 10.1016/j.virol.2022.02.005

Rotavirus Spike Protein VP4 Mediates Viroplasm Assembly by Association to Actin Filaments
Vetter, J., Papa, G., Seyffert, M., Gunasekera, K., Lorenzo, G.D., Wiesendanger, M., Reymond, J.-L., Fraefel, C., Burrone, O.R., Eichwald, C., 2022.
J Virol 96 (17):e01074-22. doi: 10.1128/jvi.01074-22

Display of Heterologous Proteins in Bacillus Subtilis Biofilms for Enteric Immunization
Aguilar, C., Wissmann, R., Fraefel, C., Eichwald, C., 2022.
Methods Mol Biol. 2465, 73-95. doi: 10.1007/978-1-0716-2168-4_4

2021

Defeating the COVID-19 pandemic with bacterial biofilms
Eichwald, C., Fraefel, C., Aguilar, C., 2021
NGZH, 166(2): 4-7. doi: 10.5167/uzh-219299

2020

Conserved Rotavirus NSP5 and VP2 Domains Interact and Affect Viroplasm
Buttafuoco, A., Michaelsen, K., Tobler, K., Ackermann, M., Fraefel, C., Eichwald, C., 2020.
J Virol 94:e01965-19. doi: 10.1128/JVI.01965-19

Mammalian orthoreovirus core protein μ2 reorganizes host microtubule-organizing center components
Eichwald, C., Ackermann, M., Fraefel, C., 2020.
Virology 549, 13-24. doi: 10.1016/j.virol.2020.07.008

Recombinant rotaviruses rescued by reverse genetics reveal the role of NSP5 hyperphosphorylation in the assembly of viral factories
Papa, G., Venditti, L., Arnoldi, F., Schraner, E.M., Potgieter, C., Borodavka, A., Eichwald, C., Burrone, O.R., 2020.
J Virol 94:e01110-19. doi: 10.1128/JVI.01110-19

2019

The Guanine Nucleotide Exchange Factor GBF1 Participates in Rotavirus Replication
Martínez, J.L., Arnoldi, F., Schraner, E.M., Eichwald, C., Silva-Ayala, D., Lee, E., Sztul, E., Burrone, Ó., López, S., Arias, C.F., 2019.
J Virol 93:e01062-19. doi: 10.1128/JVI.01062-19

2018

The dynamics of both filamentous and globular mammalian reovirus viral factories rely on the microtubule network
Eichwald, C., Ackermann, M., Nibert, M.L., 2018.
Virology 518, 77-86. doi: 10.1016/j.virol.2018.02.009

Identification of a Small Molecule That Compromises the Structural Integrity of Viroplasms and Rotavirus Double-Layered Particles
Eichwald, C., De Lorenzo, G., Schraner, E.M., Papa, G., Bollati, M., Swuec, P., de Rosa, M., Milani, M., Mastrangelo, E., Ackermann, M., Burrone, O.R., Arnoldi, F., 2018.
J Virol 92:e01943-17. doi: 10.1128/JVI.01943-17

Actin-Dependent Nonlytic Rotavirus Exit and Infectious Virus Morphogenetic Pathway in Nonpolarized Cells
Trejo-Cerro, Ó., Eichwald, C., Schraner, E.M., Silva-Ayala, D., López, S., Arias, C.F., 2018.
J Virol 92: e02076-17. doi: 10.1128/JVI.02076-17

Oral Application of Recombinant Bacillus subtilis Spores to Dogs Results in a Humoral Response against Specific Echinococcus granulosus Paramyosin and Tropomyosin Antigens
Vogt, C.M., Armúa-Fernández, M.T., Tobler, K., Hilbe, M., Aguilar, C., Ackermann, M., Deplazes, P., Eichwald, C. 2018.
Infect Immun 86(3):e00495-17. doi: 10.1128/IAI.00495-17

Mouse intestinal microbiota reduction favors local intestinal immunity triggered by antigens displayed in Bacillus subtilis biofilm
Vogt, C.M., Hilbe, M., Ackermann, M., Aguilar, C., Eichwald, C. 2018.
Microb Cell Fact 17, 187. doi: 10.1186/s12934-018-1030-8

2017

Dissection of mammalian orthoreovirus µ2 reveals a self-associative domain required for binding to microtubules but not to factory matrix protein µNS
Eichwald, C., Kim, J., Nibert, M.L., 2017.
PLoS ONE 12(9):e0184356.
doi: 10.1371/journal.pone.0184356

Rotavirus replication is correlated with S/G2 interphase arrest of the host cell cycle
Glück, S., Buttafuoco, A., Meier, A.F., Arnoldi, F., Vogt, B., Schraner, E.M., Ackermann, M., Eichwald, C. 2017.
PLoS ONE 12(6):e0179607.
doi: 10.1371/journal.pone.0179607

2016

An Inhibitory Motif on the 5'UTR of Several Rotavirus Genome Segments Affects Protein Expression and Reverse Genetics Strategies
De Lorenzo, G., Drikic, M., Papa, G., Eichwald, C., Burrone, O.R., Arnoldi, F., 2016.
PLoS One 11(11), e0166719. doi:10.1371/journal.pone.0166719

Heterologous expression of antigenic peptides in Bacillus subtilis biofilms
Vogt, C.M., Schraner, E.M., Aguilar, C., Eichwald, C., 2016.
Microb Cell Fact 15, 137. doi: 10.1186/s12934-016-0532-5

2015

Evolutionary Transitions to Multicellular Life. Principles and Mechanisms
Aguilar, C., Eichwald, C., Eberl, L., 2015
in: Ruiz-Trillo, I., Nedelcu, A.M. (Eds.), Evolutionary Transitions to Multicellular Life. Principles and Mechanisms. Springer, Dordrecht.
 pp. 79-95. doi: 10.1007/978-94-017-9642-2_4

2014

Rotavirus Increases Levels of Lipidated LC3 Supporting Accumulation of Infectious Progeny Virus without Inducing Autophagosome Formation
Arnoldi, F., De Lorenzo, G., Mano, M., Schraner, E.M., Wild, P., Eichwald, C., Burrone, O.R., 2014.
PLoS ONE 9(4):e95197.
doi: 10.1371/journal.pone.0095197

2012

Production of in vivo-biotinylated rotavirus particles
De Lorenzo, G., Eichwald, C., Schraner, E.M., Nicolin, V., Bortul, R., Mano, M., Burrone, O.R., Arnoldi, F., 2012.
J Gen Virol. 93(Pt 7): 1474-1482.
doi: 10.1099/vir.0.040089-0

Rotavirus Viroplasm Fusion and Perinuclear Localization Are Dynamic Processes Requiring Stabilized Microtubules
Eichwald, C., Arnoldi, F., Laimbacher, A.S., Schraner, E.M., Fraefel, C., Wild, P., Burrone, O.R., Ackermann, M., 2012.
PLoS ONE 7(10):e47947.
doi: 10.1371/journal.pone.0047947